Answer: ACNE

Acne is a common skin condition that occurs when hair follicles become clogged with oil and dead skin cells, resulting in the formation of pimples, blackheads, and whiteheads. It often affects teenagers and is considered a common skin woe during this stage of life.

Note: The provided meaning of the answer is for the latest New York Times crossword puzzle clue: Skin affliction. Explanations are generated by AI and may be inaccurate.