"ETS" is an acronym for "Extra-Terrestrial." In this context, "They're not from around here, in brief" suggests that it refers to beings or entities that originate from outer space or another planet.
Note: The provided meaning of the answer is for the latest New York Times crossword puzzle clue: Org. that administers the G.R.E.. Explanations are generated by AI and may be inaccurate.