The word "sciatic" refers to the sciatic nerve. It is the largest nerve in the human body and runs from the lower back down through the buttocks and down each leg. It is responsible for providing sensation and controlling the muscles of the leg and foot.
Note: The provided meaning of the answer is for the latest New York Times crossword puzzle clue: Kind of nerve that runs through the leg. Explanations are generated by AI and may be inaccurate.