Tweens refer to children who are in the age group between childhood and adolescence, typically ranging from 10 to 12 years old. They are called tweens because they are "in between" being children and teenagers. In the context of the clue, tweens are referring to the audience of the "Enola Holmes" franchise who are fans of the series.
Note: The provided meaning of the answer is for the latest New York Times crossword puzzle clue: Many fans of the "Enola Holmes" franchise. Explanations are generated by AI and may be inaccurate.