Tykes refers to young children, typically of preschool age. It can also be used informally to refer to energetic or mischievous children. The clue "Squirts" further suggests young children, as it is a colloquial term for small kids.
Note: The provided meaning of the answer is for the latest New York Times crossword puzzle clue: Squirts. Explanations are generated by AI and may be inaccurate.