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Tip: Use ? for unknown answer letters, e.g. AN??ER. Use the space bar to enter ? quickly.
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Clue: "Big bother"
"Big bother" is a New York Times crossword puzzle clue that we have seen 5 times. When there are multiple answers, the answers are sorted by the most recently seen.
Most likely answer
HEADACHE
Possible answers
HEADACHE
HASSLE
PAININTHENECK
Likely related crossword puzzle clues
Bug
Fuss
Pain
Bother
Harass
Headache
Annoyance
Inconvenience
Give a hard time
Pain in the neck
Pain in the rear
Big inconvenience
Pain in the behind
Irritating inconvenience
Getting through a busy toll plaza, e.g.
Show more
Recent usage in crossword puzzles
New York Times -
January 22, 2012
New York Times -
June 20, 2011
New York Times -
January 25, 2004
New York Times -
October 28, 2003
New York Times -
March 25, 1994