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Tip: Use ? for unknown answer letters, e.g. AN??ER. Use the space bar to enter ? quickly.
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Clue: "It's hard to get a reaction out of it"
"It's hard to get a reaction out of it" is a New York Times crossword puzzle clue that we have seen 2 times.
Possible answer
INERTGAS
Likely related crossword puzzle clues
Neon, e.g.
He is one
Krypton, e.g.
Noble thing
Neon or helium
It won't react well
Recent usage in crossword puzzles
New York Times -
December 13, 2012
New York Times -
July 30, 2011